Lipoprotein Lipase

An enzyme of the hydrolase class that catalyzes the reaction of triacylglycerol and water to yield diacylglycerol and a fatty acid anion. The enzyme hydrolyzes triacylglycerols in chylomicrons, very-low-density lipoproteins, low-density lipoproteins, and diacylglycerols. It occurs on capillary endothelial surfaces, especially in mammary, muscle, and adipose tissue. Genetic deficiency of the enzyme causes familial hyperlipoproteinemia Type I. (Dorland, 27th ed) EC 3.1.1.34.

Also Known As:

Diacylglycerol Lipase; Lipase, Lipoprotein; Diglyceride Lipase; Post-Heparin Lipase; Postheparin Lipase; Postheparin Lipoprotein Lipase; Factor, Heparin-Clearing; Factor, Lipemia-Clearing; Heparin Clearing Factor; Lipase, Diacylglycerol; Lipase, Diglyceride; Lipase, Post-Heparin; Lipase, Postheparin; Lipase, Postheparin Lipoprotein; Lipemia Clearing Factor; Lipoprotein Lipase, Postheparin; Post Heparin Lipase; Heparin-Clearing Factor; Lipemia-Clearing Factor; Triacylglycero-protein acylhydrolase

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Carboxylic Ester Hydrolases: 62
        Lipoprotein Lipase: 2175

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Drug/Important Bio-Agent (IBA)